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Services

Partnering with a network of image acquisition sites, HTI provides access to Cryo-EM resources and expertise in a fast, affordable, and scalable way, from protein purification to structure determination. By employing our solutions with your science expertise our goal is to accelerate your workflow processes for faster, more accurate acquisition and detection of your target structures.

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  • Custom Protein Production &Analysis
  • Cryo-EM Sample Optimization
  • Qualitative Sample Check
  • Real-time Al/ML Grid Processing
  • Optimized Data Collection
  • AI/ML based 2D/3D Class Selection
  • 3D Atomic Structure Determination
  • Training & Project Consultation
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Deep Cryo-EM Expertise and Resources

Scientists

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  • Experienced Cryo-EM Scientists
  • PhDs with drug discovery backgrounds
  • Industry leading cryo-EM and biomedical visionaries

Imaging

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  • High-end scopes: Krios, Glacios
  • Screening scopes: Spirit, Morgagni
  • Experienced microscopists / operators
  • Sample Prep equipment

Data Processing

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  • Senior Software Engineers and ML Engineers
  • Compute Servers and Secure Storage
  • Machine Learning based software for Automation (Proprietary)

Security

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  • Scientists on site for image processing
  • Designated sample storage
  • Controlled & Protected

Current Service Collaborators

HTI employs cryo-EM services expertise collaborating with Pharma/Biotech science expertise to enable high-resolution structure determination of drug discovery targets. Here are a few of our leading customer collaborators.

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“Working with HTI on multiple projects we have seen firsthand their level of scientific acumen, expertise and professionalism. The Cryo-EM results we received from them were key datasets within our drug discovery programs. Many thanks for all your hard work and the pleasant collaboration!” Marcin Apostol, PhD, President ADRXpharma

Why Partner with HTI on Cryo-EM?

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Fast –> Utilize expertise already in place at HTI

Affordable –> Minimize
startup costs

Scalable –> Improve throughput for incremental projects

Accelerate your structure-based drug discovery
and shorten your time to clinical trials, time to market